My name is Heng Li, a senior research scientist at the Broad Institute. I study advanced computational methods and mathematical models to help researchers to understand biology better. I have worked on genomics, population genetics, phylogenetics and network dynamics. I led the design of the SAM format, created SAMtools/htslib and developed BWA and minimap2 among others. I also routinely collaborate with other biologists and computer scientists, and have been involved in multiple international projects such as the 1000 Genomes Project.
I graduated from Nanjing University in China with a B.Sc. in physics. I obtained my Ph.D. in theoretical biophysics from the Institute of Theoretical Physics, Chinese Academy of Science, in 2006, when I worked at BGI in the same period. I was a Postdoc of Richard Durbin before moving to US in 2009.
At the time I am writing this page my wife, my daughter and I are living
around Boston, United States. Our motherland is China, forever.
- Li H. (2016) Minimap and miniasm: fast mapping and de novo assembly for noisy long sequences, Bioinformatics, 32:2103-2110. [PMID: 27153593]
- Li H., Durbin R. (2011) Inference of human population history from whole genome sequences, Nature, 475:493-436. [PMID: 21753753].
- Li H., Handsaker B., Wysoker A., Fennell T., Ruan J., et al. (2009) The Sequence alignment/map (SAM) format and SAMtools, Bioinformatics, 25:2078-2079. [PMID: 19505943]
- Li H. and Durbin R. (2009) Fast and accurate short read alignment with Burrows-Wheeler Transform, Bioinformatics, 25:1754-1760. [PMID: 19451168]